Wednesday, August 26, 2015

Story Merchant Books: FREE E-Book Deals on Amazon

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Mary Ann and Joseph Anselmo's "Through the Fire" tells the Inspirational story of her fight gainst Cancer. Coming Soon through Story Merchant Books!

Researchers treat brain cancer patient with skin cancer drug


Researchers at Memorial Sloan Kettering Cancer Center (MSK) are exploring a new form of clinical trial called a basket trial, which is designed to examine responses to drugs based on specific mutations in patients’ tumors rather than where their cancer originated.

The study, published Thursday in the New England Journal of Medicine, consisted of 122 patients from 23 cancer centers around the world, and participants were diagnosed with either non-small cell lung, colorectal, ovarian or brain cancers. Each patient had his or her tumor genome sequenced so doctors could determine which mutation to target through precision medicine, according to a news release.  

One patient in the study, MaryAnn Anselmo, had been diagnosed with stage 4 glioblastoma in 2013. Anselmo’s physicians decided to target the BRAF mutation in her tumor, and treated it with a drug recently approved for BRAF mutations in melanoma patients, TIME reported. Two years later, Anselmo is tumor free.

“This study is the first deliverable of precision medicine,” Dr. Jose Baselga, study author and MSK physician-in-chief and chief medical officer, said in the news release. “We have proven that histology-independent, biomarker-selected basket studies are feasible and can serve as a tool for developing molecularly targeted cancer therapy.”
“While we can— and should— be cautiously optimistic, this is what the future of precision medicine looks like,” he said.

Hyman told TIME that the basket study focused on BRAF mutations allows for researchers to study cancer patients as a group, despite their different diagnoses. The results found that 70 percent of patients with non-small cell cancer saw their tumors shrink by at least 30 percent in length, with the best response rate among patients with non-small cell lung cancer.

Researchers noted that the results of the study demonstrated that drugs can reach patients beyond the current approved use, but do not work for everyone. They suggest the results show the benefits of basket studies and call for more work to be done with these types of trials.
“One of the things that gets lost when we talk averages and medians is how many patients benefit and for how long,” Hyman told TIME. “There is a tremendous range and a concern that promoting the best successes sets the bar very high. But it also lets people know that things are not entirely hopeless, that there are people who have tremendous benefit from therapies and not get completely caught up in medians and averages.”

Reposted From Fox News

Story Merchant Books: FREE E-Book Deals on Amazon

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Monday, August 17, 2015

Story Merchant Books: FREE E-Book Deals on Amazon

William Diehl’s Seven Ways to Die ‪FREE‬ August 17 - 21!

Manhattan Murders ... by the book! From the New York Times bestselling author of PRIMAL FEAR and SHARKY'S MACHINE -- From the Nez Perce Indian reservation in Idaho to New York's Central Park is a straight line right through to Bill Diehl's last and most intriguing lead character, Micah Cody.

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Wednesday, August 5, 2015

Library Journal's Pick of the Month! Noire's Stone Cold Liar!

minklarueOrangeReviewStar Defending Your Castle | African American Fiction (And More!)Noire. Stone Cold Liar: The Misadventures of Mink LaRue. Dafina: Kensington.
Noire (Dirty Rotten Liar; Red Hot Liar) once again makes it a pleasure to spend time with that sneaky Mink LaRue, now living in Texas but still Harlem to the bone. Pay no mind to that apprehensive feeling this series might be growing stale. Noire keeps things moving by grabbing our attention in the first paragraph: “Me and Big Suge got buck-naked and alligator-wrestled around in his big ol’ bed.” From that you-go-girl tryst we’re off and running and nobody has sass like Mink who calls herself “Harlem’s number one stunna.” She just might be all that as she has the entire Dominion clan and their wealth on lock. Of course there’s trouble all over the Texas prairie including kidnapping, torture, revenge, harsh beat downs (both male and female), and smoking weed but not for medicinal purposes. Buckle yourselves in. This is one wild ride. VERDICT Noire has created one of the liveliest urban fiction series headed by a most memorable protagonist. Fans will get a hoot out of the biting insults and dark humor marking practically every page. This is a no-brainer purchase. If you haven’t already done so, collect the whole set.

Monday, August 3, 2015

Jerry Amernic Author of The Last Witness on Voice of Israel!

VOI's Judy Lash Balint hears from author Jerry Amernic on 'The Last Witness,' the book he wrote to counteract ignorance about WWII.
Amernic, a Canadian journalist, interviewed college students and discovered they knew nothing about the Holocaust or WWII. He explains why he thinks his novel about the last living Holocaust survivor may help preserve this important historical memory.

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Monday, July 13, 2015

KIRKUS REVIEW: David Angsten's The Assassin Lotus

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In Angsten’s (Night of the Furies, 2008, etc.) latest thriller, an American living in Italy searches for his brother and the sacred, much-desired lotus before a team of assassins can find them.

Jack Duran’s relatively quiet life as a tour guide in Rome takes a drastic turn when someone tries to kill him. A few someones, actually, who want to know about the lotus flower Jack’s paleoethnobotanist brother, Dan, sent him. Jack doesn’t know why several factions, including the U.S. Diplomatic Security Service, are interested in the lotus, but they’re sure he knows where Dan is. He doesn’t, but with a group of Iranian assassins on his tail, he decides to hunt for his brother, beginning in Turkmenistan. Jack and his brother’s girlfriend, Dutch archaeologist Phoebe Auerbach (with whom Jack was once infatuated), reconnect to track down Dan and the lotus—if they can stay alive long enough. Angsten certainly knows how to kick-start his story: Jack is on a date with mysterious Maya, unaware he’s being followed by at least two unknown parties. Angsten further establishes suspense right away with one assassin in particular, Vanitar, who blames Jack for his brother’s death and is fueled by vengeance. The book is rife with nail-biting tension, as when Jack must duck into an airport restroom before even getting out of Rome, before his and Phoebe’s search takes them inside a dark crypt. The action rarely stops. Jack (and eventually Phoebe) bounces all over Central Asia while traveling by plane, train, boat, and car. He’s also chased by professional killers, hotel security, and police in a variety of places, from a hospital to the desert. Love connections—between Jack and Phoebe as well as Dan and Phoebe—are teased, but Dan, his fate uncertain, isn’t around to ignite potential melodrama. On occasion, Angsten threatens to saturate the plot with detail—the purpose of the lotus, for example, is fairly simple and explained a bit too often—but these discussions among Jack and others are never tedious, since it’s only a matter of time before they’re back to evading murderous baddies.

Angsten hits all the genre highlights—action, suspense, mystery—in this worthwhile thriller.

Sunday, July 12, 2015

Story Merchant Books: FREE E-Book Deals on Amazon

Noire has a new deal at Book Bub!

Noire has a new deal
Natural born liar by noire and kensington publishing corporation  

Natural Born Liar

By Noire
$1.99   Originally $5.99
Available through July 31
Publisher Description
What happens when beautiful, 20-year-old petty thief and ex-stripper Mink LaRue finds out she’s a dead ringer for the age-progressed photo of the missing oil heiress Sable Dominion?
Harlem-born Mink LaRue makes a beeline... Read More >